neonatal pulmonary hypertension :: Article Creator Parents File Medical Malpractice Suit Against Columbia St. Mary's, Sixteenth Street Clinic Your browser is not supportedjsonline.Com jsonline.Com wants to ensure the best experience for all of our readers, so we built our site to take advantage of the latest technology, making it faster and easier to use. Unfortunately, your browser is not supported. Please download one of these browsers for the best experience on jsonline.Com Use Of Lung Ultrasound In Critical Ill Children With Acute Lung Disease Paediatric patients have a wide age range, a high proportion of acute diseases, insidious clinical manifestations with the limitation of monitoring means, and are prone to cardiorespiratory failure. Due to the sensitivity of paediatrics to ionising radiation is 10 times higher than that of adults, the timeliness, non-invasiveness, and dynamic assessment of critical lung ultrasound has brough
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“Young YOU| Plagues and pests | You - News24” plus 2 more
Here's more on what a plague or pestilence is, what causes it and how we might control it. (Photo: Getty Images/Gallo Images)
YOU may have heard of the 10 plagues in the Bible, or maybe you've seen news reports of locust swarms devouring crops? A plague or pest can be human and/or natural – in other words it might occur only in animals, only in humans or in both. Two terms can help you understand plagues and pestilence better: mass sickness (epidemic) and devastation.
Here's more on what a plague or pestilence is, what causes it and how we might control it.
A plague can be plants that cause damage to crops (noxious weeds); vertebrates such as rodents or birds; invertebrates such as insects, fleas or snails; or nematodes (roundworms). When a plague comes in the form of a pathogen (bacteria, virus or fungus), we call it pestilence, and this can cause outbreaks of mass sickness (epidemic or pandemic). Plagues can also come in the form of organisms that affect water quality and cause damage to animals or other parts of the ecosystem, leading to widespread devastation.
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Plague is one of the deadliest diseases in human history, second only to smallpox. A bacterial infection found mainly in rodents and associated fleas, plague readily leaps to humans in close contact. Plague outbreaks are the most notorious epidemics in history, inciting fears of plague's use as a biological weapon.
Today, plague cases still pop up sporadically around the world—including in the United States or China, where a suspected case was recently reported in the Inner Mongolia region. But the disease is no longer as deadly as it can be treated with antibiotics when available.
Here's what you need to know about the plague, including how it spreads, the difference between bubonic and pneumonic plague, the most infamous plague pandemics in history, and why it's not all that unusual to see modern cases of the disease.
Stages of plague
For hundreds of years, what caused plague outbreaks remained mysterious, and shrouded in superstitions. But keen observations and advances in microscopes eventually helped unveil the true culprit. In 1894, Alexandre Yersin discovered the bacterium responsible for causing plague: Yersinia pestis.
Y. pestis is an extraordinarily virulent, rod-shaped bacterium. Y. pestis disables the immune system of its host by injecting toxins into defense cells, such as macrophages, that are tasked with detecting bacterial infections. Once these cells are knocked out, the bacteria can multiply unhindered.
Many small mammals act as hosts to the bacteria, including rats, mice, chipmunks, prairie dogs, rabbits, and squirrels. During an enzootic cycle, Y. pestis can circulate at low rates within populations of rodents, mostly undetected because it doesn't produce an outbreak. When the bacteria pass to other species, during an epizootic cycle, humans face a greater risk for becoming infected with plague bacteria.
Rats have long been thought to be the main vector of plague outbreaks, because of their intimate connection with humans in urban areas. Scientists have more recently discovered that a flea that lives on rats, Xenopsylla cheopis, primarily causes human cases of plague. When rodents die from the plague, fleas jump to a new host, biting them and transmitting Y. pestis. Transmission also occurs by handling tissue or blood from a plague-infected animal, or inhalation of infected droplets.
Bubonic plague, the disease's most common form, refers to telltale buboes—painfully swollen lymph nodes—that appear around the groin, armpit, or neck. The skin sores become black, leading to its nickname during pandemics as "Black Death." Initial symptoms of this early stage include vomiting, nausea, and fever.
Pneumonic plague, the most infectious type, is an advanced stage of plague that moves into the lungs. During this stage, the disease is passed directly, person to person, through airborne particles coughed from an infected person's lungs.
Three particularly well-known pandemics occurred before the cause of plague was discovered. The first well-documented crisis was the Plague of Justinian, which began in 542 A.D. Named after the Byzantine emperor Justinian I, the pandemic killed up to 10,000 people a day in Constantinople (modern-day Istanbul, Turkey), according to ancient historians. Modern estimates indicate half of Europe's population—almost 100 million deaths—was wiped out before the plague subsided in the 700s.
Arguably the most infamous plague outbreak was the so-called Black Death, a multi-century pandemic that swept through Asia and Europe. It was believed to start in China in 1334, spreading along trade routes and reaching Europe via Sicilian ports in the late 1340s. The plague killed an estimated 25 million people, almost a third of the continent's population. The Black Death lingered on for centuries, particularly in cities. Outbreaks included the Great Plague of London (1665-66), in which 70,000 residents died.
The cause of plague wasn't discovered until the most recent global outbreak, which started in China in 1860 and didn't officially end until 1959. The pandemic caused roughly 10 million deaths. The plague was brought to North America in the early 1900s by ships, and thereafter spread to small mammals throughout the United States.
The United States, China, India, Vietnam, and Mongolia are among the other countries that have had confirmed human plague cases in recent years. Within the U.S., on average seven human cases of plague appear each year, emerging primarily in California and the Southwest.
Today, most people survive plague with rapid diagnosis and antibiotic treatment. Good sanitation practices and pest control minimize contact with infected fleas and rodents to help prevent plague pandemics.
Plague is classified as a Category A pathogen, because it readily passes between people and could result in high mortality rates if untreated. This classification has helped stoke fears that Y. pestis could be used as a biological weapon if distributed in aerosol form. As a small airborne particle it would cause pneumonic plague, the most lethal and contagious form.
Of conservation concern, federally endangered black-footed ferrets contract another form of the plague, sylvatic plague, from nearby prairie dogs. Plague can decimate prairie dog populations, which are a critical food source for black-footed ferrets. Scientists have started to administer a vaccine to prevent plague outbreaks in prairie dogs and black-footed ferrets.
This story has been updated. It was originally published on August 20, 2019.
UNIVERSITY PARK, Pa. — An outbreak of the highly pathogenic avian influenza virus in poultry in 2014-15 resulted in the destruction of more than 50 million chickens and turkeys in the U.S., causing billions of dollars in economic loss. This animal disease outbreak — the worst in U.S. history — is one example of how devastating a foreign animal disease can be to animal agriculture and the country's economy. The resurgence of avian influenza in multiple states, including Pennsylvania, is once again bringing the importance of preventing animal diseases to the forefront, noted Suresh Kuchipudi, clinical professor of microbiology in Penn State's College of Agricultural Sciences. Exploring the emergence, spread and control of animal infectious diseases such as avian influenza was the focus of the inaugural Emerging Animal Infectious Disease Conference held Nov. 29-Dec.1, 2021, at Penn State. It was hosted by the College of Agricultural Sciences, the Pennsylvania Department of A
dented can botulism :: Article Creator Three Canadians Sickened In France's Botulism Outbreak Are From Quebec: PHAC The Public Health Agency of Canada has confirmed that the three Canadians who fell ill in a botulism outbreak in France are from Quebec. They're among at least 12 people who have suspected botulism after eating sardines prepared and served at Tchin Tchin Wine Bar in Bordeaux, France. The food was eaten between Sept. 4 and Sept. 10. The Associated Press has reported that some patients have been released from hospital, but most of them are in intensive care or critical condition. Canada's public health agency says it cannot divulge the condition of the patients from Quebec because it is considered private health information. Other tourists from the U.S., Ireland, Germany and Spain were among those sickened. One patient, who was not from Canada, has died. France's public health agency is leading the investigation
“Live Coronavirus Map Used to Spread Malware - Krebs on Security” plus 1 more Live Coronavirus Map Used to Spread Malware - Krebs on Security Posted: 12 Mar 2020 05:12 PM PDT Cybercriminals constantly latch on to news items that captivate the public's attention, but usually they do so by sensationalizing the topic or spreading misinformation about it. Recently, however, cybercrooks have started disseminating real-time, accurate information about global infection rates tied to the Coronavirus/COVID-19 pandemic in a bid to infect computers with malicious software. A recent snapshot of the Johns Hopkins Coronavirus data map, available at coronavirus.jhu.edu. In one scheme, an interactive dashboard of Coronavirus infections and deaths produced by Johns Hopkins University is being used in malicious Web sites (and possibly spam emails) to spread password-stealing malware. Late last month, a member of several Russian language cybercr
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