The mere mention of the word “plague” conjures up some ghastly images, even among the most hardened of infectious disease specialists. After all, it’s not every communicable disease that earns the moniker “Black Death.” So, it’s no surprise that news from China last week regarding 2 new confirmed cases of pneumonic plague—the most deadly of the 3 known forms of the disease, along with bubonic and septicemic, caused by bacterium Yersinia pestis —has generated global headlines . “Cases [of the plague] continue to occur around the world, and there are some hotspots,” Ashok Kumar Chopra, CSc, PhD, professor, Department of Microbiology & Immunology, and member, Center for Biodefense and Emerging Infectious Diseases, University of Texas Medical Branch, told Contagion ®. “When they occur of course people get worried about it because they are aware of how dangerous it can be.” Of course, this is hardly the first outbreak of pneumonic plague since the disease ravaged the global populatio...