NATIONAL HARBOR, Md. -- Many patients with Trypanosoma cruzi infection, or Chagas disease, in Los Angeles had multiple other comorbidities, a researcher said here. In a multivariable analysis, both cardiomyopathy and age were significant predictors of multiple comorbidities in these patients, reported Salvador Hernandez, MD, of the Centers of Excellence for Chagas Disease in Sylmar, California. More than half of patients with Chagas disease had two or more comorbidities, he noted at a presentation at the American Society of Tropical Medicine & Hygiene annual meeting. Although Chagas disease is often thought of as a parasitic infection that predominantly affects rural areas of Latin America, Hernandez noted a large epidemiological burden of cases in the U.S., including an estimated 70,000 in California, 37,000 in Texas, 18,000 in Florida, and 17,000 in New York, none of which included undocumented individuals. However, he added that Chagas disease is severely underdiagnosed i...