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black plague treatment :: Article Creator Black Death Vaccine Being Developed Amid Fears The Disease Could Return And Kill Millions COVID jab scientists are developing a Black Death vaccine over fears the disease could re-emerge and kill millions. Researchers believe their inoculation will be the first approved in the UK for the ancient infection. 1 Covid jab scientists are developing a Black Death vaccineCredit: Getty The Black Death — also known as bubonic plague — has killed 200million people worldwide and medics fear a super-strength version may now appear. The team behind the Oxford AstraZeneca coronavirus vaccine said they had made progress on an injection that could prevent bubonic plague developing. A trial of their vaccine on 40 healthy adults, which started in 2021, shows it is safe and can produce an immune response to the often-fatal condition. Prof Sir Andrew Pollard, director of the Oxford Vaccine Group, said the t...
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Plagues Speed Up With Each New Outbreak - MedicineNet

Plagues Speed Up With Each New Outbreak - MedicineNet

Plagues Speed Up With Each New Outbreak - MedicineNet

Posted: 19 Oct 2020 12:00 AM PDT

Latest Infectious Disease News

News Picture: In Medieval Times, Plagues 'Sped Up' With Each New Outbreak

TUESDAY, Oct. 20, 2020

Medieval plague outbreaks in England picked up frightening speed in the 17th century, Canadian researchers report.

Their analysis of historical documents covering 300 years showed that outbreaks of the plague doubled every 11 days in London during the 1600s, compared to every 43 days in the 14th century.

"It is an astounding difference in how fast plague epidemics grew," said lead author David Earn, an investigator with the Michael G. DeGroote Institute for Infectious Disease Research at McMaster University in Hamilton, Ontario.

No published death records were available for London before 1538.

So statisticians, biologists and evolutionary geneticists analyzed personal wills, parish registers and data used to monitor burials in London to estimate death rates. During medieval times, people typically wrote wills because they were dying or feared imminent death, so those were "a good proxy for the spread of fear and of death itself," Earn said in a university news release.

Previous genetic studies identified the pathogen that causes plague, including the Black Death of 1348, which killed more than one-third of Europe's population, and the Great Plague of 1665. But little was known about how the disease was transmitted.

This research suggests that it was not spread by human-to-human transmission. Growth rates for both epidemics are more consistent with bubonic plague, which is transmitted by bites of infected fleas, the researchers said.

They suspect population density, living conditions and cooler temperatures could explain the rapid acceleration.

"From genetic evidence, we have good reason to believe that the strains of bacterium responsible for plague changed very little over this time period, so this is a fascinating result," said study co-author Hendrik Poinar, a professor of anthropology at McMaster.

Earn, Poinar and their colleagues said lessons of the past can be applied to modern-day pandemics like COVID-19. They developed a digitized archive that provides a way to analyze past patterns in search of new information about the spread of infectious disease.

The findings were published Oct. 19 in the Proceedings of the National Academy of Sciences.

-- Cara Roberts Murez

MedicalNews
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SOURCE: McMaster University, news release, Oct. 19, 2020
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