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pulmonary venous hypertension :: Article Creator Insmed Stock Soars On Pulmonary Arterial Hypertension Drug Trial Results Shares of Insmed (INSM) jumped nearly 30% Tuesday after the biopharmaceutical company reported positive results from a Phase 2 trial for its treatment of pulmonary arterial hypertension. The Bridgewater, N.J.-based company said the study was "evaluating the efficacy and safety of treprostinil palmitil inhalation powder" in patients with pulmonary arterial hypertension, or PAH, and that the trial "met its primary endpoint and all secondary efficacy endpoints." Pulmonary hypertension, which develops when the blood pressure in your lungs is higher than normal, affects about 1% of people globally, per the National Heart, Lung, and Blood Institute. Insmed said it would "immediately engage with the U.S. Food and Drug Administration (FDA) regarding the Phase 3 trial design for PAH. Insmed plans to in...

Album Review: Mastiff – Plague - Kerrang!

The English Mastiff is a gentle giant of the canine world, known for its calm demeanour and gentle, loving nature. Not these Hull miserabilists, however. Picking up where 2017’s Bork EP left off, Plague explodes like a grind-sludge Molotov cocktail; its vision of humanity as disease burning with fury, anguish and frustration.

From the roller-coaster downward spiral of Hellcircle, through Bubonic’s ear-shattering powerviolence, to 69-second nightmare Brainbleed, there’s nowhere to hide, before nine-minute closer Black Death blots out any last remaining light with a rising tide of apocalyptic doom. Shades of grind pioneers Napalm Death, aggro-tastic U.S. brutalists Nails and the swampy, kaleidoscopic acid-trip imagery of Crowbar bleed through everywhere, and within the churning pestilence and pervasive darkness, Mastiff’s message stands out in big letters: they’re fucked, and we are too.

Verdict: KKKK
Words: Sam Law



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