contagious bacteria in stool :: Article Creator C. Diff Infection: Symptoms, Causes, Diagnosis And Treatment Clostridioides difficile (C. Diff) is a type of bacteria that can cause colitis, a serious inflammation of the colon. Infections from C. Diff often start after you've been taking antibiotics. It can sometimes be life-threatening. When you have C. Diff, the symptoms can range from mild to severe. Mild symptoms can include problems such as: Watery diarrhea that happens three to four times a day for several days Stomach pain, cramping, or tenderness In more serious infections, there may be blood or pus in the stool. This can happen because C. Diff can cause the colon (also called the large intestine) to get inflamed. When this happens, tissue in the colon can bleed or make pus. Other symptoms of a serious infection include: If your C. Diff infection is severe, you could get severe intestinal inflammation. Your colon could als...