chronic lung disease symptoms :: Article CreatorLung Disease News
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Sep. 25, 2024 — Researchers have tested a combination of treatments in mice with lung cancer and shown that these allow immunotherapies to target non-responsive ...
Sep. 19, 2024 — Scientists are now able to directly compare the different kinds of injury that mechanical ventilation causes to cells in the lungs. In a new study, using a ventilator-on-a-chip model, researchers ...
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COPD News
Mar. 10, 2023 — One in 10 adults suffer from the debilitating effects of chronic obstructive pulmonary disease (COPD). Research around a new breathing device developed by pulmonologists offers promise for improving ...
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Dec. 5, 2022 — A six-month study oncludes that the use of portable home air purifiers can improve some markers of cardiovascular health in people with chronic obstructive pulmonary disease, or ...
Nov. 23, 2022 — Sometimes healthcare professionals treat patients with opioids such as morphine to relieve symptoms, but there has been a lack of evidence as to whether this helps with severe chronic breathlessness. ...
Nov. 15, 2022 — Airway inflammation and emphysema are more common in marijuana smokers than cigarette smokers, according to a new study. Researchers said the difference may be due to the way that marijuana is smoked ...
Sep. 5, 2022 — Researchers have found that dual bronchodilators -- long-lasting inhalers that relax the airways and make it easier to breathe -- do little to help people who do not have chronic obstructive ...
Aug. 2, 2022 — Structural differences in lung airways between men and woman may be the cause of differences in chronic obstructive pulmonary disease (COPD) prevalence and outcomes between the sexes. According to a ...
July 25, 2022 — Idiopathic pulmonary fibrosis (IPF) is an aging-associated disease caused by progressive scarring of the lungs, leading to respiratory failure and death. Therapies to treat IPF are limited, making ...
June 21, 2022 — Study into the consequences of childhood infection finds Australian children who had bronchitis at least once before the age of seven were more likely to have lung problems in later ...
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May 3, 2022 — Initial tests of a new 'crystal ball' for COPD revealed that it is better at predicting risk for both African-Americans and heavy smokers than existing ...
Apr. 1, 2022 — A new type of cell that resides deep within human lungs and may play a key role in human lung diseases has been ...
Mar. 30, 2022 — Scientists show how cells packed with SARS-CoV-2 detach from the upper airway and spread deep into lungs where severe COVID can take root. They also discovered how an asthmatic reaction to allergens ...
Mar. 28, 2022 — A significant amount of genetic risk for asthma is likely mediated through altered gene expression within the airway epithelium. That is the conclusion of a new study to identify genetic variants ...
Mar. 23, 2022 — The lower airways of patients with cystic fibrosis (CF) have unique biochemical features that correlate with the complex communities of lung bacteria typical of this disease, according to a ...
Mar. 23, 2022 — Scientists have developed a drug to treat the uncontrolled secretion of mucins in the airways, which causes potentially life-threatening symptoms in millions of Americans with lung ...
Mar. 15, 2022 — Disease of the small airways in the lungs is a potential long-lasting effect of COVID-19, according to a new study. The study found that small airways disease occurred independently of initial ...
Feb. 23, 2022 — Obesity has been linked to a wide array of health problems. A new study suggests that abdominal obesity as measured by body mass index (BMI) and waist circumference, may result in a greater risk of ...
Jan. 27, 2022 — A team of researchers has identified previously unrecognized changes in gene expression and cellular interactions in distinct cell populations in chronic obstructive pulmonary disease ...
How Do Smoking Cessation Programs Help Manage COPD Symptoms?
Smokers' airways are hyper-reactive, meaning they sometimes can be hyper-responsive to non-noxious stimuli also, and smoking cessation is found to prevent further progression of airway hyper-responsiveness.
Written by Tavishi DograUpdated : December 31, 2024 1:43 AM IST
Smoking is the most critical; thus, it is of paramount importance to consider smoking cessation as it is the only intervention. Cigarette smoke contains 1000s of noxious gases and particles like Co2, CO, oxides of nitrogen, and sulfur. These harmful particles, on inhalation, act on the airway cells to incite an inflammatory reaction. This inflammatory reaction is characterized by an influx of cells and cellular products, various chemical mediators secreted by these cells, and the normal respiratory epithelial cells. These chemical mediators and inflammatory cells bring out many changes in the airway wall structure and function. Some of which are transient, and some are permanent.
Effects Of Smoking In COPD
Some of the effects are an increase in the number and size of the mucosal glands, which makes them secrete more viscous and comparatively more significant amounts of mucus. This viscous mucus is one reason for caroming cough and sputum production in smokers, and when it persists for a long time, it causes chronic bronchitis. The noxious particles from the fumes also damage delicate hair-like structures on the respiratory epithelium called cilia. They help clear respiratory secretions and any foreign particles, including bacteria and viruses, that gain entry into the respiratory tract. Damage to these cilia means incomplete clearance of the secretions and increased susceptibility to infection. These inflammatory changes, when left unchecked for many years due to chronic smoking, can cause permanent changes in the airway architecture, making the disease process irreversible. The breathing tubes become narrow and fixed, causing breathlessness and wheezing, characteristics of COPD. This inflammation also damages the air sac, affecting the gas exchange and in advance disease; this is the reason for low oxygen and increased carbon dioxide in the body. How Do Smoking Cessation Programs Help Manage COPD Symptoms?
Depending on the degree of smoking history, the inflammation in the airway may or may not completely reverse. However, studies have found a significant reduction in smokers' symptoms after stopping smoking. They report fewer episodes of cough, sputum production, and wheezing. Due to breathlessness's multifactorial nature, the effects of smoking cessation on breathlessness may be variable. Hence, some people may perceive improvement in breathlessness after quitting smoking, and some may not. The improvement in symptoms is more profound in smoking cessation in people who have not developed significant airflow limitations before quitting. Smoking also causes an accelerated decline in lung function, and quitting smoking can slow this rate of decline in lung function. Some studies have shown normalization of the rate of lung function decline after 2 years of quitting. Conclusion
However, the architectural changes in the airway structure brought on by chronic inflammation, such as mucus gland enlargement, airway wall fibrosis, air sac wall damage, and loss of airway attachment, may not be completely reversible when smoking is stopped. This is the cause of COPD's irreversible nature.
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