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tb gold test :: Article Creator Scientists Develop A TB Test & Find A Genetic Vulnerability In Resistant Strains A rapid diagnostic test for tuberculosis (TB) has been approved for the first time by the World Health Organization (WHO). The assay can identify the tuberculosis-causing pathogen Mycobacterium tuberculosis in sputum samples within a few hours. Tuberculosis is a primary cause of death by infectious disease worldwide. The disease is estimated to kill over one million people every year, and is a huge socio-economic burden, particularly in low- and middle-income countries. "High-quality diagnostic tests are the cornerstone of effective TB care and prevention," said Dr. Rogerio Gaspar, WHO Director for Regulation and Prequalification. "Prequalification paves the way for equitable access to cutting-edge technologies, empowering countries to address the dual burden of TB and drug-resistant TB."  M. Tuberculosis c...

What Was the Black Death, and Where Did It Originate? - The Vintage News

The Black Death was a fatal disease that caused the demise of somewhere between 75 and 200 million people throughout Eurasia, having the most lethal impact on Europe. It is said to have been so deadly that it set Europe back 150 years. Although scientists have long known how the disease was transmitted to humans, they now also know where it emerged in the 1300s. Before this discovery, it was still a mystery where the disease started before it reached other parts of the world. 

What was the Black Death?

The Black Death swept through the world between 1346 and 1353. The disease earned its sinister name because some people infected with the illness experienced the death of body parts, like fingers, which turned black and gangrenous. The bacteria that caused the Black Death most commonly manifested as the bubonic plague, named after the large, swollen lymph nodes all over the victim's body. 

Coloured drawing of two shirtless men, part of a flagellant sect, whipping themselves to atone for the plague.

Flagellant sect whipping themselves to save them from God's wrath, manifested in the form of the plague. (Photo Credit: Ann Ronan Pictures/ Print Collector/ Getty Images)

The Black Death was not something that people of the time had encountered, so they did not know what caused it or how to fix it. It led them to believe many eccentric theories about why there was a plague. Perhaps the most extreme were flagellants, who believed that the disease was a punishment from God. To atone for their sins, they would repeatedly whip themselves in public. 

Black and white drawing of a plague doctor, wearing long robes, a beaked mask, and a hat.

A plague doctor in protective clothing. The mask held spices thought to purify air, the wand was used to avoid touching patients, c. 1656. (Photo Credit: Hulton Archive/ Getty Images)

Others believed that the sickness was caused by bad air. Plague doctors, one of the most commonplace images associated with the Black Death, subscribed to the belief that the plague spread this way. They would wear beaked masks which would be filled with scented items so that they could not smell the "bad air," and therefor wouldn't get sick.

Where did it come from?

Before this recent research, there was disagreement over where the Black Death originated. Some believed that it originated with the Mongol Army along the Silk Road trading routes, while others believed it originated in Europe. Historical evidence has always pointed toward the Black Death originating in the East of Eurasia. 

Coloured photo of a map showing the Silk Road trading route.

Fabric showing the Silk Road. (Photo Credit: Pool BENAINOUS/ TINACCI/ Gamma-Rapho/ Getty Images)

Researchers now suspect that the Black Death originated in North Kyrgyzstan, a country in Central Asia, in the late 1330s. This research was conducted by a team of scientists from Scotland's University of Stirling and Germany's Max Planck Institute and University of Tübingen. They analyzed DNA from skeletons at Lake Issyk Kul in the Tian Shan region of Kyrgyzstan.

The new research

Dr. Phillip Slavin from the University of Stirling identified an increased number of deaths in two cemeteries, in Kara-Djigach and Burana, between 1338 and 1339. Ten tombstones there even made reference to a "pestilence," a word often used when describing the Black Death. Once they visited the cemeteries, researchers took DNA samples from the teeth of seven bodies. Three of those bodies carried Yersinia pestis, which is the bacteria that caused the Black Death. 

Black and white photo through a microscope of the Yersina Pestis bacteria

Yersinia pestis bacteria, the cause of bubonic plague. (Photo Credit: IMAGE POINT FR/ NIH/ NIAID/ BSIP/ Universal Images Group/ Getty Images)

Although the bodies that researchers studied contain the bacteria associated with the Black Death, they are also located in an area that would have allowed the disease to spread to other parts of Eurasia. The region is part of the historic Silk Road which would mean that traders frequently passed through the area. 

More from us: How the Worst Pandemics in History Finally Ended

This is backed up by the presence of pearls from the Indian Ocean, as well as coral from the Mediterranean being present inside some of the graves in the region. Slavin explained, "We can hypothesize that trade, both long distance and regional, must have played an important role in spreading the pathogen westward."

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