lung cancer stages :: Article Creator Real-World Practice Upholds Lobectomy For Early-Stage Lung Cancer LOS ANGELES -- Surgeries to remove small tumors in stage IA non-small cell lung cancer (NSCLC) were associated with varying odds of long-term survival depending on the amount of lung removed, based on real-world data collected from across the country. In routine practice, unadjusted 10-year overall survival (OS) for lobectomy reached 44.8%, while for segmentectomy it was 44.2%, and for wedge resection 41.4%, according to Christopher Seder, MD, of Rush University Medical Center in Chicago, at the annual meeting of the Society of Thoracic Surgeons (STS). Lobectomy was associated with a significantly lower risk of all-cause mortality relative to sublobar resections in general (HR 0.87, 95% CI 0.83-0.92), though on closer inspection, this was really an advantage over wedge resections (HR 0.84, 95% CI 0.80-0.88) but not segmentectomy (HR 0.96, ...
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“The Emperor Strikes Back: ‘Star Wars’ Resurrects Palpatine (Again) - The Ringer” plus 2 more
On Monday, Lucasfilm unleashed a trailer for The Rise of Skywalker that started with Luke looking at the twin suns of Tatooine, sped through the story of the first eight Star Wars movies (sans spinoffs) in roughly 60 seconds, and transitioned seamlessly into scenes from no. 9, due out on December 20. The montage made the saga—the product of five different directors over five different decades—look like a cohesive whole, not least because the brand-new footage bore so many ties to the first two trilogies. Thirsty Star Wars fans drank in Chewie, Leia, and C-3P0; the Millennium Falcon's remote droid; Rey's red, double-bladed lightsaber; a cavalcade of classic spacecraft, including Y-Wings, B-Wings, a Corellian corvette, and a fleet of old-school, Imperial-era Star Destroyers; the ruins of the second Death Star; and, most prominently, Emperor Palpatine (played by the indomitable Ian McDiarmid), who croaks the trailer's only previously unheard line, "Your journey nears its end."
Palpatine's presence became clear in the film's first teaser, which featured a shot of the Death Star II's superstructure and closed with Palpatine's trademark cackle. At that point, it still wasn't clear how much we would see of the dearly departed Darth Sidious, who appeared to perish when he plunged into the Death Star's reactor core at the climax of Return of the Jedi. Now, though, it looks like he'll play a central role. In addition to owning the trailer's signature speaking part, Palpatine looms behind a dueling Rey and Kylo Ren in the Rise of Skywalker poster, and Daisy Ridley confirmed that the character is "very instrumental to the plot of the film."
In a sense, everything is proceeding as J.J. Abrams observers have foreseen. The nostalgia-dependent director covered Steven Spielberg in 2011's Super 8, brought back Khan in 2013's Star Trek Into Darkness, and borrowed lovingly and liberally from the first Star Wars movie in 2015's The Force Awakens, so it's hardly surprising that he's dipping into the past once again for the final film in the Skywalker nonology. Abrams had originally planned to bring back the Death Star in The Force Awakens before settling for another massive, circular superweapon instead. And according to Lucasfilm president Kathleen Kennedy, Palpatine's reappearance has been in the works for a while.
Kathleen Kennedy says Palpatine's return was in the blueprint for a long time. "We had not landed on exactly how we might do that, but it was always [to be in Episode IX]." pic.twitter.com/SDqqKHgJ7C
For fans of the franchise who are tired of recycling—and who welcomed Rian Johnson's willingnesstosubvert the series' tropes in The Last Jedi—Palpatine part deux is predictably derivative. Last weekend, series star John Boyega hyped Palpatine's comeback by invoking the idea of defeating the Emperor properly, and Kelly Marie Tran hinted that Palpatine's new plot line evokes her favorite Star Wars theme: redemption. But both destruction and redemption are things we thought Luke and Anakin accomplished when they took down Palpy in the first place.
In Abrams's defense, though, he isn't the first Star Wars storyteller to resurrect Palpatine. The concept of bringing back the Emperor played a pivotal role in restarting the Star Wars franchise after the dormant decade that followed the end of the original trilogy. Retracing the steps that restored him the first time around may help explain Abrams's impulse to extend his story—and, perhaps, shed a little light on what's in store for Mr. Sidious (known as Sheev to his friends).
Dark Horse Comics
Palpatine's first second life began with a letter to George Lucas. Inspired in part by the 1987 release of Star Wars: The Roleplaying Game, Tom Veitch, the writer of a six-part comic series called The Light and Darkness War that was published by Marvel imprint Epic Comics from 1988-89, wrote to Lucas on November 19, 1988. Marvel's original run of Star Wars comics had ended in 1986, and the Ewoks and Droids series published by another Marvel imprint, Star Comics, had ended in 1987, so the Star Wars comics license had lapsed. Veitch proposed a new series, in which he and his collaborator, artist Cam Kennedy, would take to Epic if the creator of Star Wars signed off. "In those days EVERYTHING went across the desk of George Lucas," Veitch says via email.
As Veitch was walking to the post office, he heard John Williams's main theme to Star Wars emanating from an open window, which he took as an auspicious sign. Three days later, he got a call saying that Lucas wanted to see his work, and a week after that, Lucas offered him and Kennedy the Star Wars comics franchise. Veitch relayed the offer to Epic editor Archie Goodwin—a former Star Wars comics writer himself—who seized the opportunity. The idea developed into Dark Empire, a six-issue series published by Dark Horse Comics (which picked up the project after Lucasfilm pulled the license from Marvel) from 1991-92 and followed by the six-issue sequel Dark Empire II in 1994-95 and the two-issue conclusion Empire's End in 1995.
Dark Horse Comics
Veitch wanted to tell momentous, significant stories about Star Wars, and he first pitched a series called "The Jedi Chronicles" that would trace the history of the Jedi order. Although that idea later turned into another Veitch-authored series, Tales of the Jedi, it didn't pass muster with The Flannelled One at first, perhaps in part because Veitch had expressed interest in focusing on the decades after the Clone Wars. Lucas was already planning the prequels, so he told Veitch to attempt no landings there. Instead, he directed him to the era after the original trilogy. "George gave us 'carte blanche' (his words) to make up a story that took off from the end of Return of the Jedi," Veitch writes in an excerpt he sent us from an in-progress book about Star Wars that he's planning to publish next year.
Goodwin suggested constructing a post-Jedi series around an impostor inside the suit of Darth Vader, and Veitch wanted to "put a weak indecisive man inside the Vader costume … and create a tension between the fearsome image and the 'man within.'" (Sounds familiar.) Lucas, reluctant to tamper with Vader's legacy, vetoed that too. But, Veitch recalls, Lucas offered an alternative, replying, "If you can figure out a way to bring back the Emperor, you can do that."
The comic creators embraced Lucas's suggestion. "The obvious idea," Veitch says, "was that Emperor Palpatine had been cloning himself for quite a while, inhabiting each clone in succession through the dark power of the Force." Lucas liked that idea, and he also approved bringing back Boba Fett and letting Luke temporarily succumb to the Dark Side as the reborn Emperor's apprentice. That conflict became the basis of Dark Empire.
Dark Horse Comics
"Substitute villains who are similar to old villains can be OK, but usually you have to spend a lot of time making people believe in them," Veitch says. "Our idea was to build on the power that the Emperor … already held over the viewer's imagination. And rather than having a new character try to convert Luke to the Dark Side, we would show that the very essence of the Dark Side—the Emperor—still lives, more powerful than ever."
Not everyone welcomed this conceit. Author Timothy Zahn, whose landmark bookHeir to the Empire arrived months before Dark Empire and helped bridge the narrative gap between Return of the Jedi and Veitch's series, raised the obvious objection that resurrecting the Emperor contradicted and undermined Jedi's ending (although Vader's sacrifice is still stirring despite his boss's hidden backup body). But Veitch had an alternate interpretation of the events in the Death Star's throne room.
Dark Horse Comics
In Veitch's telling, the Emperor egged on Luke to strike him down not because he knew Vader would intercept Luke's slash, but because he was indifferent to his physical fate (much like Obi-Wan was when he dared Vader to do the striking). Veitch theorized that Palpatine had emerged from his fortress on Coruscant only because his young clone was complete. If Luke gave in to temptation, it would accomplish two goals: pulling his potential apprentice toward the Dark Side and freeing the decrepit Palpatine to transition to his heathy clone body. To Veitch, then, the blue flash that follows Palpatine's free fall "represented the Emperor's living energy, his conscious dark force, leaving his body." According to Veitch's vision, the Emperor's consciousness "was translated across the Galaxy almost instantaneously and entered a new youthful body," which would enable Palpatine to "live forever … and perhaps rule the Empire for thousands of years."
Veitch says there wasn't a widespread backlash to Palpatine's reappearance, noting, "I think most people got it that a burnt-out old Sith can't rule a galaxy for very long unless he's figured out a way to prolong his life." Although he says he sympathizes with anyone who disagreed with the decision, he argues that the detractors "were probably unfamiliar with the history of movie serials and comics, where great villains never completely die—they always return." As Veitch points out, Star Wars was partly based on Flash Gordon, "in which the principal villain, the evil emperor Ming the Merciless, is never completely killed off." That argument might be music to Abrams's ears.
Dark Horse Comics
Like the rest of the expanded universe that sprung up around Star Wars in the decades before Disney bought the franchise from Lucas, Dark Empire was decanonized in 2014. But many characters and concepts from the EU proved too beloved not to bring back and have since crossed over into the current canon. Dark Empire's legacy lives on in a variety of Veitch ideas, from a crash-landed Star Destroyer to the Galaxy Gun, which anticipated Starkiller Base's ability to destroy planets from afar. Luke's dalliance with the reborn Emperor could be echoed in a similar struggle for Rey, and Veitch also envisioned a son of Leia and Han, named Anakin, who would "embody both the light and dark aspects of the Skywalker lineage and suffer great inner conflict in his life." The prequels cemented Palpatine's desire to cheat death. (Did you ever hear the tragedy of Darth Plagueis the Wise?) And now, The Rise of Skywalker will return him to life.
In December, we'll find out what form that life takes and how closely The Rise of Skywalker's portrayal of Palpatine mirrors Dark Empire's. Based on what we've seen so far, it seems unlikely that the Emperor's comeback will be based on cloning technology: On the poster and in the teaser and trailer, he looks and sounds as old as he was when we last saw him alive, and it's not clear why he would have waited more than 30 years to make his presence known if he'd had a healthy body in storage.
Dark Horse Comics
It's possible The Rise of Skywalker's Emperor is a pretender (another old EU idea) or a simulacrum stored in a Sith relic (an EU idea also). The final season of Star Wars Rebels, which belongs to the current canon, introduced a form of time travel, which could conceivably come into play. More likely, Palpatine's disembodied dark essence survives, possibly bound to the bones of the Death Star. From that remote location, he may have possessed a puppet—perhaps Supreme Leader Snoke—and orchestrated the First Order's rise in secret, which is consistent with his pattern of masking his power plays. With Snoke dead, he could hope to transfer his spirit into the body of Kylo or Rey (who could be a clone herself). Dark Empire foreshadowed that too: "Another idea we had," Veith says, "was that Palpatine simply used a secret Sith power to possess a new body." In Dark Empire, Palpy tries to send his spirit into the infant Anakin after Han blasts his last body, but he's blocked by the life force of a dying Jedi, who drags him into oblivion.
Dark Horse Comics
In recent years, Star Wars books, comics, and video games have laid a little groundwork for the Emperor redux. Marvel's Darth Vader comics reestablished the concept of a Sith lord preserving himself in a relic and inhabiting the bodies of others. Several sources explain that Palpy left a plan, called the "Contingency," which would destroy the dying remnants of the Empire and hasten its rebirth as the First Order. He also seeded the galaxy with dangerous dark side relics and Imperial technology, including the Eclipse, which served as Palpatine's flagship in Dark Empire and, according to the current canon, was sent to the Unknown Regions where the First Order formed. The 2016 novel Aftermath: Life Debtnotes that only 75 percent of the Empire' Star Destroyers were confirmed captured or destroyed; the other quarter could be the faithful fleet floating in a space storm in the latest trailer, awaiting orders from its Emperor.
"Part of the story of this movie is history repeats itself," Abrams said of The Force Awakens in 2015. Repetition is part of the story of The Rise of Skywalker, too—and, frankly, of the franchise as a whole. In the case of posthumous Palpatine, though, that story started on the page long before it leaped onto the screen.
Star Wars continues to induce fans to scream out for answers. In Star Wars: The Rise of Skywalker, did Emperor Palpatine use the power Darth Plagueis taught him to resurrect himself and create powerful Force users, one of which we know as Rey? (Many versions of the Force users could look like Rey. The new trailer for The Rise of Skywalker offers a new Rey; see below.)
Kylo Ren and Rey duel with lighstabers amidst a tumultuous body of water. (Disney/Lucasfilm)
Palpatine knows how to use the dark magic of creating life
In Star Wars: Episode III – Revenge of the Sith, Palpatine tells Anakin Skywalker about how Darth Plagueis the Wise knew this power. Palpatine also said that Plagueis taught his apprentice everything Plagueis knew. It's canon (see the book Tarkin) that that apprentice is Palpatine himself.
It stands to reason that he could thus bring himself back and certainly create more powerful Force users. I say "more" because he already used the power in the canon to create Anakin Skywalker (see Darth Vader #25).
Image: Lucasfilm Publishing
So it seems clear that Palpatine did this with Rey. Did he deploy the power en masse with Reys? (Perhaps because he improve in the skill enough to duplicate his work?) This would split the difference between Rey not turning evil in the 11th hour but also there legitimately being on the dark side.
If Palpatine used his power to create Rey and all the versions of her, reports that Palpatine is Rey's father makes sense
We saw a tweet during Disney D23 Expo 2019 from a journalist who was told by a Disney security guard that Palpatine is Rey's father. This would also explain a scene in Star Wars: The Last Jedi where Rey sees many versions of herself. This could also be our answer as to Rey's mysterious origins. And yes, JJ Abrams has said that while he will honor Rian Johnson's answer as to Rey's parents as seen in The Last Jedi, he is going to provide more information about that.
Consider also how lifeless and cold the "dark side Rey" looked. Could it be because she is as much creation-template as human?
(Both Anakin and Rey being a Palpatine creation also speaks to the theory that Rey was the reincarnated Chosen One.)
What do you think about this theory? How is Palpatine alive again when he seemed to have died in Star Wars: Return of the Jedi? Does Palpatine's power explain "dark side Rey?" Comment below. And check out the new trailer for The Rise of Skywalker begging the question about multiple Reys.
It's not easy to hide things from today's fans. Marvel didn't say a word about Avengers: Endgame being a time travel movie, and yet every MCU fan went in expecting it, because they'd trawled the trailers and set photos and costume designs and simply figured it out. But Lucasfilm managed to keep the fact that Emperor Palpatine was making a return in Star Wars: The Rise of Skywalker a secret from fans.
10 Getting thrown into a reactor core by Darth Vader
Palpatine managed to service Darth Vader's character development across the Star Wars saga by simply being way more evil than him. He was hitting Luke with Force lightning, and it was sadistic enough to snap Vader out of his Dark Side tendencies and get him to pick up Palpatine and toss him down a reactor core, sacrificing himself to save his only son. What makes this moment even more impressive on Palpatine's part is the fact that he somehow managed to survive the fall – or live on from beyond the grave – and make it to the events of The Rise of Skywalker, several decades later.
9 "Power! Unlimited Power!"
Some of the impact of this scene is lessened by the fact that Samuel L. Jackson and George Lucas have both since agreed that Mace Windu survived the fall. Still, it's an important moment, because it's the clearest moment that we see Anakin abandon the Light Side of the Force and turn to the Dark Side. Palpatine is hitting Windu with Force lightning and Windu is deflecting it back into his face.
Anakin can only choose to save one of them, and with Palpatine promising him "unlimited power," he decides to save him, sending Windu flying out into the Coruscant skyline.
8 Persuading Anakin to kill Count Dooku
The opening scene of Revenge of the Sith gave us one of the greatest space battles in Star Wars history. Three movies in, George Lucas finally learned how to use CGI effects as an improvement, rather than a hindrance. It sees Obi-Wan and Anakin infiltrating a Separatist ship in order to rescue a captured Palpatine.
The two Jedi Knights have to battle Count Dooku to get to Palpatine, and at the end of the fight, Anakin has Dooku on his knees, ready to be decapitated. The Jedi don't kill unless it's absolutely necessary, and in this case, it's not necessary – but Palpatine tells Anakin, "Do it," and he does.
7 Encouraging Luke Skywalker and Darth Vader to fight
The greatest strength of the Palpatine character is his ability to manipulate other people's motivations and behavior. For years, he was the puppet-master behind Darth Vader, telling him what to do and what to think. In the climactic battle sequence in Return of the Jedi, he manipulates a lightsaber duel between Luke and Vader. When Luke arrives at the Emperor's throne room, he doesn't want to fight Vader.
But because Vader is under the Emperor's thumb, a fight breaks out anyway. The perfect shot to symbolize this is the closeup of a smiling Emperor as Luke and Vader's lightsabers clash in front of his face.
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6 Telling Anakin the story of Darth Plagueis
One of the most controversial things that Disney did after purchasing Lucasfilm to alienate Star Wars fans was throw out the Expanded Universe – novels, comic books, and video games that these fans had invested years in and hundreds of creators had cultivated to build a wider Star Wars universe, and the Mouse House just tossed it in the trash.
Thankfully, Darth Plagueis, possibly the most powerful Sith Lord who ever lived, made his way into canon when Palpatine told his story to Anakin in Revenge of the Sith. The scene is even more powerful, because it hints at Palpatine being Anakin's father.
5 Taking on four Jedi Knights singlehandedly
When Palpatine's evil plan becomes apparent to the Jedi Council, it's not long before Mace Windu, Kit Fisto, Saesee Tiin, and Agen Kolar all head down to his office to bring him to justice. However, as the mild-mannered, if a little dodgy politician reveals himself to be the Sith Lord they call Darth Sidious, the Jedi realize they're in serious trouble.
These are highly trained, powerful, experienced Jedi Knights, and Windu is the only one that it takes Palpatine more than a few seconds to strike down. The threat of Darth Sidious escalates exponentially within moments and even Mace Windu himself panics.
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4 Hitting Luke with Force lightning
We were first introduced to the concept of Force lightning in Return of the Jedi, and it was pretty awesome. We'd seen that the Force could be used to move things around or sense that loved ones were in danger, which is how the Jedi use it, but then we saw that the Sith have much cooler applications for it, like shooting lightning out of their fingers.
It's a gut-wrenching scene, because Luke Skywalker is the heart of this saga and, as it came to its conclusion, it was looking like our hero might not make it to the end.
3 Executing Order 66
As soon as the Galactic Senate's vote goes through and Palpatine assumes control of the entire Republic, he contacts Commander Cody and tells him, "Execute Order 66." This turns out to be the mass murder of every Jedi Knight currently in the field. A huge part of Palpatine's plan involved wiping out the Jedi, because they were the only force in the galaxy that posed a threat to him.
One of the greatest moments in Revenge of the Sith – and bear in mind that this is a movie with a very high great moment quotient – is the moment at which Anakin Skywalker truly becomes Darth Vader. He'd already turned his back on the Jedi and been seduced by the Dark Side, but when he awakens in that black suit with Palpatine at his side is the moment he really embodies Vader for the first time.
The final nail in Anakin's coffin is when Palpatine tells him he murdered his wife, and the tragedy is that this isn't even true; he just said it to kill whatever shred of Anakin might have remained.
1 His lightsaber duel with Yoda
It wasn't until Revenge of the Sith that we really saw Palpatine in action. Until then, we knew him as the crotchety old man pulling the strings behind Darth Vader in the original trilogy and a politician stuck behind a desk in the other prequels. But in Revenge of the Sith, he takes on Yoda in one of the most breathtaking lightsaber duels in Star Wars history.
UNIVERSITY PARK, Pa. — An outbreak of the highly pathogenic avian influenza virus in poultry in 2014-15 resulted in the destruction of more than 50 million chickens and turkeys in the U.S., causing billions of dollars in economic loss. This animal disease outbreak — the worst in U.S. history — is one example of how devastating a foreign animal disease can be to animal agriculture and the country's economy. The resurgence of avian influenza in multiple states, including Pennsylvania, is once again bringing the importance of preventing animal diseases to the forefront, noted Suresh Kuchipudi, clinical professor of microbiology in Penn State's College of Agricultural Sciences. Exploring the emergence, spread and control of animal infectious diseases such as avian influenza was the focus of the inaugural Emerging Animal Infectious Disease Conference held Nov. 29-Dec.1, 2021, at Penn State. It was hosted by the College of Agricultural Sciences, the Pennsylvania Department of A...
dented can botulism :: Article Creator Three Canadians Sickened In France's Botulism Outbreak Are From Quebec: PHAC The Public Health Agency of Canada has confirmed that the three Canadians who fell ill in a botulism outbreak in France are from Quebec. They're among at least 12 people who have suspected botulism after eating sardines prepared and served at Tchin Tchin Wine Bar in Bordeaux, France. The food was eaten between Sept. 4 and Sept. 10. The Associated Press has reported that some patients have been released from hospital, but most of them are in intensive care or critical condition. Canada's public health agency says it cannot divulge the condition of the patients from Quebec because it is considered private health information. Other tourists from the U.S., Ireland, Germany and Spain were among those sickened. One patient, who was not from Canada, has died. France's public health agency is leading the investigation...
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